It is this that in large part has guided the development of the Israeli Air Force (IAF) over recent years.
The IAF has purchased 125 advanced F-15I and F-16I warplanes, equipped with Israeli avionics and additional fuel tanks - tailor-made for long-range strike missions.
In addition, Israel has bought specialised bunker-busting munitions; developed large, long-endurance, unmanned aircraft; and much of its training has focused on long-range missions.
Israel has a track-record of pre-emptive strikes against nuclear targets in the region.
Remains of the Osirak nuclear site outside Baghdad (2002) Israel has a track-record of pre-emptive strikes against nuclear targets
In June 1981, Israeli jets bombed the Osirak reactor near the Iraqi capital, Baghdad.
More recently, in September 2007, Israeli warplanes attacked a facility in Syria that Israel, the US and many experts believed was a nuclear reactor under construction.
However, a potential strike against Iran would be nothing like the attacks in Iraq and Syria. These were both against single targets, located above ground, and came literally out of the blue.
An Israeli attempt to severely damage Iran's nuclear programme would have to cope with a variety of problems, including range, the multiplicity of targets, and the nature of those targets.
Many of these problems are daunting in themselves, but when put together, they only compound the difficulties facing Israeli military planners.
How to get there?
For a start it is a very long way from Israel to Iran. As a rough estimate many of the potential targets are some 1,500km (930 miles) to 1,800km (1,120 miles) from Israeli bases. Israeli warplanes have to get to Iran and, equally important, get back.
At least three routes are possible.
* There is the northern one where Israeli jets would fly north and then east along the borders between Turkey and Syria, and then Turkey and Iraq
* The central, more likely route would take Israeli warplanes over Iraq. With the US military gone, the Iraqi authorities are far less able to monitor and control their air space, effectively opening a door to an Israeli incursion
* The third, southern route would take Israeli jets over Saudi air space. Would the Saudis turn a blind eye to such a move given their own concerns about Iran's nuclear programme? Could this route be used by Israeli aircraft on the return leg of their journey? We just do not know
Map showing possible routes Israeli aircraft might take to bomb Iranian nuclear sites
What we do know, given the range, is that Israeli aircraft will have to be topped up with fuel en route.
Douglas Barrie, senior fellow for military aerospace at the International Institute for Strategic Studies (IISS) in London, says that "air-to-air refuelling will be critical".
Israeli F-15 fighter jets refuel during an air show at the graduation ceremony of Israeli pilots in the Hatzerim air force base in the Negev desert near the southern Israeli city of Beersheva on June 30, 2011 Israel is believed to have between eight and 10 large tankers based on the Boeing 707 airframe
"Israeli aircraft," he says, "need not just to get in and out of Iranian air space; they need to have enough fuel to provide time over their targets and they need sufficient fuel to cover any contingencies that might arise during the mission."
The initial tanking, Mr Barrie says, might be done over the Mediterranean or even in Israeli airspace. "One option," he notes, "would be to take off with a full bomb load and drop tanks containing additional fuel; to climb to cruising altitude and then at this point to replenish their tanks, before setting course for their targets in Iran."
Israel is believed to have between eight and 10 large tankers based on the commercial Boeing 707 airframe, but experts believe that tanking capacity will prove one of the limiting factors in the scope of any operation.
What targets to hit?
The problems of range, the nature of some of the targets, and the availability of tanker aircraft will determine the nature and scope of any Israeli operation.
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Iran nuclear sites
Douglas Barrie, of the IISS, says that "Israeli planners will be looking for where they can do most damage with the limited number of platforms at their disposal".
"They'll be asking where the main choke points are in the Iranian programme. Clearly, striking enrichment facilities makes a lot of sense from a military point of view," he adds.
So the uranium enrichment facilities at Natanz, south of Tehran, and Fordo, near the holy city of Qom, would almost certainly be prominent on the target list.
The heavy-water production plant and heavy-water reactor under construction at Arak, in the west, might also figure, as would the uranium conversion facility at Isfahan.
It is unclear whether Israel would have the capacity to strike a range of other targets associated with Iran's missile programmes and explosives testing.
But this target list raises another set of problems. The enrichment facilities at Natanz are underground and the new plant at Fordo is buried deeply into the side of a mountain.
Can Israel destroy buried targets?
For an attack like this, says Douglas Barrie, you need good intelligence information. "You need to know", he says, "about the geography of the target site; its geology; the nature of the earth; and the details of the design and construction of any buried reinforced concrete chambers."
"You can assume," he asserts, "that the Americans and the Israelis have been watching these sites closely over time."
The target would have to be attacked from relatively close range, meaning any attacking force will have to fight its way in and out of heavily-contested airspace”
End Quote Robert Hewson IHS Jane's Air-Launched Weapons
To reach buried targets you need special kinds of munitions. Deeply-buried facilities are not exclusive to the Middle East. There is a kind of race between the diggers and the weapons designers and it is one where the Americans have considerable experience.
The main weapon in Israel's arsenal is the US-supplied GBU-28. This is a 5,000lb (2,268kg) laser-guided weapon with a special penetrating warhead. For an assessment of its capabilities I turned to Robert Hewson, the editor of IHS Jane's Air-Launched Weapons.
"The GBU-28," he told me, "is the largest penetrating weapon available for a tactical aircraft and, since it was first used by the US in 1991, it has been improved with better warheads and more accurate guidance.
"However, Israel's use of this weapon would be hindered by several key operational factors. Realistically, the F-15I - the only delivery platform - can carry only one bomb, so a sizeable attack force would be required - demanding tanker and other support assets that Israel does not have in large numbers.
"The target would have to be attacked from relatively close range, meaning any attacking force will have to fight its way in and out of heavily-contested airspace."
Furthermore, he says that "very accurate targeting data is required to use a weapon like GBU-28 to best effect".
"The potential for success of a GBU-28 attack is not determined by the 'book' performance of the weapon alone."
Of course, the great unknown question is how capable these weapons would be against buried Iranian enrichment facilities at Natanz and Fordo.
1. The bombs are carried by Israeli F-15Is - but only one per aircraft, which would mean a large attack force for multiple attempts on numerous targets
2. Bomb is released almost vertically over the target, and guided by lasers
3. The bombs can penetrate up to 6m of concrete or about 30.5m of earth before detonating the 4,400lb warhead
Mr Hewson says that the GBU-28 is "effective against any hardened or deeply buried target - up to a point".
"For a weapon like the GBU-28, velocity and angle of impact determine the penetrating effect, so the ideal drop is made from high altitude at maximum speed and hits the target at a near vertical angle," he explains.
"This is less easy to do against a cave or mountainside, so the weapon will be less effective - but still more effective than pretty much any other available munitions."
Indeed, as Douglas Barrie notes, one weapon might be insufficient.
"You could", he says, "attempt to 'dig your way in' using several weapons on the same impact area to try to get through the soil, rock and concrete. Or you could try to block access to the facility by destroying tunnel entrances.
"In addition," he says, "all of these facilities are power hungry, so you could attempt to destroy power supplies and any buried cabling.
"The aim would be to present the Iranians with a compound problem of blocked entrances, no power and collapsed underground chambers."
Does Israel have other military options?
So far we have discussed only the known elements of Israel's capabilities, mainly US-supplied aircraft and munitions. But Israel has a hugely advanced aerospace and electronics industry of its own and this may well have produced systems relevant for an attack against Iran.
The Eitan, the Israeli Air Force's latest generation of Unmanned Aerial Vehicle (UAV), flies over a ceremony introducing it into the 210th UAV squadron on February 21, 2010 at the Tel Nof air base in central Israel. The Eitan, or Heron TP, weighs in at 5,000 kgs and has a 26 meter wingspan. It can carry a heavy payload, is equipped with more advanced technological systems than its predecessors and has a 20-hour high-altitude flying time. The Eitan, the Israeli Air Force's latest generation of Unmanned Aerial Vehicle
Douglas Barrie says that there is much about Israel's capabilities, especially its home-grown technology, that we do not know.
"Israel's long-range Heron or Eitan drone could be used to gather an assessment of the damage done by any strikes, but perhaps could also be put to use helping to spoof air defences," he adds.
"Indeed, this kind of deception or cyber-operation will likely be an integral part of the mission with the aim of blinding radars or generating a false picture of what was going on."
What about Iran's air defences?
Iran's air defences are largely Russian-supplied systems familiar to Israeli pilots, though Iran also deploys the US-built Hawk system dating back to the days of the Shah.
Iran's defences
Hawk surface-to-air missiles (bottom-C) are seen in Khandab near Arak, 290 kms (180 miles) southwest of the Iranian capital Tehran, during military manoeuvres on November 26, 2009.
Surface-to-air missiles - Hawk system (pictured)
For high altitude targets - SA-5 or S-200
For low level targets - Tor-M1/SA-15 Gauntlet
Long-range systems - S-300
Iranian Air Force - Russian-built Mig-29s, US-built F-14 Tomcats
Some of its most capable defences are Russian SA-5 missiles intended to target high-altitude threats, while it also deploys the mobile Tor-M1/SA-15 Gauntlet system optimised to engage targets at lower level.
Russia has consistently refused to supply Iran with the much more capable S-300 long-range system, though the Iranians claim to have procured some batteries elsewhere.
Iran's surface-to-air missile force may be old but still represents a threat. Look at how much effort Nato and the US put into taking down Libya's similar vintage air defences last year.
Israel will not have the time or the resources to embark upon this kind of protracted air campaign and thus the electronic element of any strike to suppress Iranian defences is likely to be as important as the actual dropping of weapons.
Israel's small submarine force could potentially play a role here too. Douglas Barrie says that "there must be a reasonable assumption that Israel has an operational sea-launched cruise missile capability based upon their German-built Dolphin submarines".
Escorted by navy missile ships, Israeli submarine 'Dolphin' sails along the Mediterranean Sea near the coastal city of Tel Aviv during special naval maneuvers ahead of Israel?s 60th independence anniversary on May 5, 2008. The 'Dolphin', a German-built submarine, is 56.4m long with a cruising range of 4500 nautical miles. It is armed with ten 21-inch multi-purpose tubes for torpedoes, mines, missiles and decoys. Israel's small submarine force could play a role
"These could be used to go after older but capable SA-5 air defence sites and big search and surveillance radars."
But, he notes: "Adding a naval dimension complicates the co-ordination of any attack."
Iran's air force is seen by experts as being totally outclassed by its Israeli counterpart.
It has a small number of US-built F-14 Tomcat fighters and a significant number of relatively more modern Russian-supplied MiG-29s.
But the potential threat from Iranian aircraft again complicates Israeli planning and any air-to-air combat might place additional strains on the limited fuel supplies carried by the attacking aircraft.
Would an Israeli strike succeed?
Most experts agree that Israel could hit multiple targets in Iran and do considerable damage to its nuclear programme. They would, however, do much less damage than a full-scale US attack using all of the resources at Washington's disposal.
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“Start Quote
Even if successful, it would only delay Iran's nuclear programme”
End Quote Douglas Barrie International Institute for Strategic Studies
The Israelis would be operating at the very limits of their capabilities. "If they pulled it off," says Douglas Barrie, "it would be an impressive display of power projection against a difficult and dispersed set of targets."
Only a small number of air forces in the world, he notes, could mount such an operation. But, Mr Barrie stresses: "Even if successful, it would only delay Iran's nuclear programme."
It is a point echoed by IHS Jane's Robert Hewson.
"Israel does not have the mass of forces and will not be given the operational freedom [by Iran] required to destroy Iran's nuclear complex," he says. "If you bury enough stuff deep enough, enough of it will survive. Any Israeli attack can only damage and possibly not even slow the Iranian effort.
"The consequences of such an attack would be dire and global. It is impossible to see any up-side to this venture."
That's a view shared for now by Israel's most important ally.
Only a few days ago, the Chairman of the US Joint Chiefs of staff, Gen Martin Dempsey, said that an Israeli attack would not be prudent.
Such a strike, he said, "would be destabilising and would not achieve their long-term objectives".
However Israel's calculus is very different. Knowing all their operational limitations, might they launch such an operation anyway?
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