The uprising in Egypt has created turmoil for Israeli and Palestinian leaders, who have their own complicated relationships with the Mubarak regime.

For Prime Minister Benjamin Netanyahu of Israel, President Hosni Mubarak has been his strongest ally in the region. At the same time, Mr. Mubarak has been a firm ally of the Palestinian Authority and a staunch supporter of the stalled Israeli-Palestinian peace process. Egypt has also tried to broker reconciliation talks (so far, unsuccessfully) between Fatah, the party governing the West Bank, and Hamas, which controls Gaza.

What does the crisis in Egypt mean for the Israeli-Palestinian negotiations? How crucial is Mr. Mubarak to dialogue between Israel and its neighbors? Will change in the Egyptian regime make progress in Mideast peace talks even less likely?