A Palestinian man was seriously wounded after being stabbed in an attack carried out by Jews in Occupied Jerusalem on Wednesday, officials said.

Police were searching for a number of suspects who stabbed the 31-year-old resident of East Jerusalem, an Israeli police spokesman said.

The man told Israel police four men wearing skullcaps attacked him near the ultra-Orthodox Jewish neighbourhood of Mea Shearim.

The spokesman did not confirm the attackers were Jews, but said police believed it was a "nationalistically motivated" assault.